Another Test for Cocaine Addiction Exercise 7.42 on page 532 describes an
experiment on helping cocaine addicts break the cocaine addiction, in which
cocaine addicts were randomized to take desipramine, lithium, or a placebo.
The results (relapse or no relapse after six weeks) are summarized in Table
\(7.38 .\)
(a) In Exercise 7.42, we calculate a \(\chi^{2}\) statistic of 10.5 and use a
\(\chi^{2}\) distribution to calculate a p-value of 0.005 using these data, but
we also could have used a randomization distribution. How would you use cards
to generate a randomization sample? What would you write on the cards, how
many cards would there be of each type, and what would you do with the cards?
(b) If you generated 1000 randomization samples according to your procedure
from part (a) and calculated the \(\chi^{2}\) statistic for each, approximately
how many of these statistics do you expect would be greater than or equal to
the \(\chi^{2}\) statistic of 10.5 found using the original sample?
$$
\begin{array}{l|cc|c}
\hline & \text { Relapse } & \text { No Relapse } & \text { Total } \\
\hline \text { Desipramine } & 10 & 14 & 24 \\
\text { Lithium } & 18 & 6 & 24 \\
\text { Placebo } & 20 & 4 & 24 \\
\hline \text { Total } & 48 & 24 & 72
\end{array}
$$