An experiment to evaluate whether vitamins can help prevent recurrence of
blocked arteries in patients who have had surgery to clear blocked arteries
was described in the article "Vitamins Found to Help Prevent Blocked Arteries"
(Associated Press, September 1, 2002). The study involved 205 patients who
were given either a treatment consisting of a combination of folic acid,
vitamin B 12, and vitamin B6 or a placebo for 6 months.
a. Explain why a placebo group was used in this experiment.
b. Explain why it would be important for the researchers to have assigned the
205 subjects to the two groups (vitamin and placebo) at random.
c. Do you think it is appropriate to generalize the results of this experiment
to the population of all patients who have undergone surgery to clear blocked
arteries? Explain.