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Magnet Treatment of Pain People spend around $5 billion annually for the purchase of magnets used to treat a wide variety of pains. Researchers conducted a study to determine whether magnets are effective in treating back pain. Pain was measured using the visual analog scale, and the results given below are among the results obtained in the study (based on data from “Bipolar Permanent Magnets for the Treatment of Chronic Lower Back Pain: A Pilot Study,” by Collacott, Zimmerman, White, and Rindone, Journal of the American Medical Association, Vol. 283, No. 10). Higher scores correspond to greater pain levels.

a. Use a 0.05 significance level to test the claim that those treated with magnets have a greater mean reduction in pain than those given a sham treatment (similar to a placebo).

b. Construct the confidence interval appropriate for the hypothesis test in part (a).

c. Does it appear that magnets are effective in treating back pain? Is it valid to argue that magnets might appear to be effective if the sample sizes are larger?

Reduction in Pain Level after Magnet Treatment: n = 20, x = 0.49, s = 0.96

Reduction in Pain Level after Sham Treatment: n = 20, x = 0.44, s = 1.4

Short Answer

Expert verified

a. There is insufficient evidence that the magnet’s treatment is better than sham’s treatment in reducing pain.

b. The 90% confidence interval for this test is (-0.61,0.71).

c. It appears that the magnet’s treatment is not effective enough in treating the back pain. If the sample size increases, then it might be helpful to use the magnet’s treatment in treating back pain.

Step by step solution

01

Given information

The effectiveness of magnet treatment at a 0.05 level of significance is to be tested. The statistics are stated below.

\(\begin{array}{l}{{\rm{1}}^{{\rm{st}}}}\;{\rm{sample}}\;{\rm{:magnet's treatment}}\\{n_1}\; = 20,\\{s_1} = 0.96\;\\{{\bar x}_1} = 0.49\end{array}\)

\(\begin{array}{l}{{\rm{2}}^{{\rm{nd}}}}\;{\rm{sample}}\;{\rm{:sham}}\left( {{\rm{placebo}}} \right){\rm{ treatment}}\\{n_2} = 20\;\\{s_2} = 1.4\;\\{{\bar x}_2} = 0.44\end{array}\)

02

State the hypothesis

To test the claim that the magnet treatment reduces pain better, the hypotheses are stated as follows:

\(\begin{array}{l}{H_{0\;}}:{\mu _1} = {\mu _2}\\{H_1}\;:{\mu _1} > {\mu _2}\end{array}\)

Here,\({\mu _1},{\mu _2}\)are the population means of pain reduction after magnet treatment and sham treatment, respectively.

The test is right tailed.

03

State the test statistic

This is an example of two independent sample t-test concerning means.

The formula for t-statistics is given below.

\({t_{stat}} = \frac{{\left( {{{\bar x}_1} - {{\bar x}_2}} \right) - \left( {{\mu _1} - {\mu _2}} \right)}}{{\sqrt {\frac{{s_1^2}}{{{n_1}}} + \frac{{s_2^2}}{{{n_2}}}} }}\)

04

Find degrees of freedom, critical value

For t-distribution, find the degrees of freedom as follows:

\(\begin{array}{c}df = \min \left( {\left( {{n_1} - 1} \right),\left( {{n_2} - 1} \right)} \right)\\ = \min \left( {\left( {20 - 1} \right),\left( {20 - 1} \right)} \right)\\ = 19\end{array}\)

The critical values are obtained as follows:

\(\begin{array}{c}P\left( {t > {t_\alpha }} \right) = \alpha \\P\left( {t > {t_{0.05}}} \right) = 0.05\end{array}\)

Thus, the critical value obtained from the t-table for 19 degrees of freedom is 1.729.

05

Compute test statistic

The test statistic of the means of populations is as follows:

\(\begin{array}{c}t = \frac{{\left( {{{\bar x}_1} - {{\bar x}_2}} \right)}}{{\sqrt {\frac{{s_1^2}}{{{n_1}}} + \frac{{s_2^2}}{{{n_2}}}} }}\\ = \frac{{\left( {0.49 - 0.44} \right)}}{{\sqrt {\frac{{{{\left( {0.96} \right)}^2}}}{{20}} + \frac{{{{\left( {1.4} \right)}^2}}}{{20}}} }}\\ = 0.132\end{array}\)

The test statistic is \(t = 0.132\).

06

Decision rule using the critical value

The decision criterion for this problem statement is given below.

If thetest statistic is greater than the critical value, reject the null hypothesis at \(\alpha \)level of significance.

If the test statistic is lesser than critical value, indicates failure to accept the null hypothesis at \(\alpha \)level of significance.

Here\(\left| {{t_{stat}} = 0.132} \right|\; < \;{t_{crit}} = 1.729\). Thus, there is a failure to reject the null hypothesis.

It indicates that the magnet’s treatment is ineffective relative to sham’s treatment.

07

Confidence interval for the difference of means of population

b.

For the 0.05 level of significance, the appropriate confidence level is 90%.

The formula for the confidence interval of the means of population is given by

\(\left( {{{\bar x}_1} - {{\bar x}_2}} \right) - E < \left( {{\mu _1} - {\mu _2}} \right) < \left( {{{\bar x}_1} - {{\bar x}_2}} \right) + E\)

E is the margin of error, and the formula for the margin of error is as follows:

\(\begin{array}{c}E = {t_{\frac{\alpha }{2}}} \times \sqrt {\frac{{s_1^2}}{{{n_1}}} + \frac{{s_2^2}}{{{n_2}}}} \\ = {t_{\frac{{0.10}}{2}}} \times \sqrt {\frac{{{{0.96}^2}}}{{20}} + \frac{{{{1.4}^2}}}{{20}}} \\ = 1.729 \times 0.3795\\ = 0.656\end{array}\)

Substitute the values in the formula to find the confidence interval.

\(\begin{array}{c}{\rm{C}}{\rm{.I}} = \left( {{{\bar x}_1} - {{\bar x}_2}} \right) - E < \left( {{\mu _1} - {\mu _2}} \right) < \left( {{{\bar x}_1} - {{\bar x}_2}} \right) + E\\ = \left( {0.49 - 0.44} \right) - 0.656 < \left( {{\mu _1} - {\mu _2}} \right) < \left( {0.49 - 0.44} \right) + 0.656\\ = - 0.61 < \left( {{\mu _1} - {\mu _2}} \right) < 0.71\end{array}\)

Since 0 is included in the confidence interval, the result is the same as part(a).

Thus, there is insignificant difference in the reduction of pain using magnet treatment.

08

Analyze the results

c.

The magnets are not effective in treating back pain.

In this case, the sample sizes are 20. There appears to be a possibility that larger sample sizes may result in better results.

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Most popular questions from this chapter

In Exercises 5–20, assume that the two samples are independent simple random samples selected from normally distributed populations, and do not assume that the population standard deviations are equal. (Note: Answers in Appendix D include technology answers based on Formula 9-1 along with “Table” answers based on Table A-3 with df equal to the smaller of\({n_1} - 1\)and\({n_2} - 1\).)

Seat Belts A study of seat belt use involved children who were hospitalized after motor vehicle crashes. For a group of 123 children who were wearing seat belts, the number of days in intensive care units (ICU) has a mean of 0.83 and a standard deviation of 1.77. For a group of 290 children who were not wearing seat belts, the number of days spent in ICUs has a mean of 1.39 and a standard deviation of 3.06 (based on data from “Morbidity Among Pediatric Motor Vehicle Crash Victims: The Effectiveness of Seat Belts,” by Osberg and Di Scala, American Journal of Public Health, Vol. 82, No. 3).

a. Use a 0.05 significance level to test the claim that children wearing seat belts have a lower mean length of time in an ICU than the mean for children not wearing seat belts.

b. Construct a confidence interval appropriate for the hypothesis test in part (a).

c. What important conclusion do the results suggest?

Braking Reaction Times: Boxplots Use the same data from Exercise 6 and use the same scale to construct a boxplot of the braking reaction times of males and another boxplot for the braking reaction times of females. What do the boxplots suggest?

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Testing Claims About Proportions. In Exercises 7–22, test the given claim. Identify the null hypothesis, alternative hypothesis, test statistic, P-value or critical value(s), then state the conclusion about the null hypothesis, as well as the final conclusion that addresses the original claim.

Clinical Trials of OxyContin OxyContin (oxycodone) is a drug used to treat pain, butit is well known for its addictiveness and danger. In a clinical trial, among subjects treatedwith OxyContin, 52 developed nausea and 175 did not develop nausea. Among other subjectsgiven placebos, 5 developed nausea and 40 did not develop nausea (based on data from PurduePharma L.P.). Use a 0.05 significance level to test for a difference between the rates of nauseafor those treated with OxyContin and those given a placebo.

a. Use a hypothesis test.

b. Use an appropriate confidence interval.

c. Does nausea appear to be an adverse reaction resulting from OxyContin?

Before/After Treatment Results Captopril is a drug designed to lower systolic blood pressure. When subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results are given in the accompanying table (based on data from “Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Converting Enzyme,” by MacGregor et al., British Medical Journal, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that captopril is effective in lowering systolic blood pressure?

Subject

A

B

C

D

E

F

G

H

I

J

K

L

Before

200

174

198

170

179

182

193

209

185

155

169

210

After

191

170

177

167

159

151

176

183

159

145

146

177

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