Phagocytosis is a type of endocytosis where the cell ingests large particles, such as bacteria, dead cells, or other sizable objects. This mechanism is critical for the immune system, as it helps in removing pathogens and cellular debris. During phagocytosis, the cell's membrane engulfs the target particle, forming a phagosome which is then internalized.
Important aspects of phagocytosis include:
- Ingestion of solids: Unlike pinocytosis, phagocytosis targets large particles.
- Selective process: Cells often recognize specific particles to ingest, usually tagged by molecules such as antibodies.
- Phagosome formation: The engulfed particle is enclosed in a membrane-bound vesicle known as a phagosome.
Phagosomes usually fuse with lysosomes, resulting in the digestion of the engulfed material. Phagocytes, for instance, are specialized cells that perform phagocytosis, playing a pivotal role in the immune response by defending the body against infections.