Chapter 9: Problem 1
Haptens A. can function as antigens. B. strongly bind to antibodies specific for them. C. may be macromolecules. D. never act as antigenic determinants. E. can directly clicit the production of specific antibodies.
Chapter 9: Problem 1
Haptens A. can function as antigens. B. strongly bind to antibodies specific for them. C. may be macromolecules. D. never act as antigenic determinants. E. can directly clicit the production of specific antibodies.
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Get started for freeAll of the following are characteristic of serine proteases as a class except A. only one serine residue is catalytically active. B. natural protein substrates and inhibitors bind very tightly to the protease. C. the genes that code for serine proteases are organized in a similar fashion. D. catalytic units exhibit two structural domains of dramatically different size. E. conversion of zymogen to active enzyme usually involves one or more hydrolytic reactions.
One of the adaptations to high altitude is an increase in the concentration of BPG. What effect does this have on a saturation versus \(p \mathrm{O}_{2}\) curve? Why does increasing [BPG] increase the delivery of \(\mathrm{O}_{2}\) to tissues?
In immunoglobulins all of the following are true except A. there are four polypeptide chains. B. there are two copies of each type of chain. C. all chains are linked by disulfide bonds. D. carbohydrate is covalently bound to the protein. E. immunoglobulin class is determined by the \(\mathrm{C}_{\mathrm{L}}\) regions.
Myoglobin has a Hill coefficient of 1.0 and hemoglobin has a Hill coefficient of \(2.8 .\) This indicates that A. an oxygen saturation curve for myoglobin would be sigmoidal. B. hemoglobin exhibits a simple equilibrium binding of oxygen. C. myoglobin shows negative cooperativity in its binding of oxygen. D. hemoglobin shows positive cooperativity in its binding of oxygen. E. only myoglobin would yicld a straight line in a Hill plot.
Hemoglobin and myoglobin both have, are, can, or do all of the following except A. subunits that provide hydrogen bonds to and nonpolar interaction with other subunits. B. highly \(\alpha\) helical. C. bind one molecule of heme per globin chain. D. bind heme in a hydrophobic pocket. E. bind one \(\mathrm{O}_{2}\) per heme.
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