Chapter 8: Problem 5
A number of specific sequences have been found in many promote and operator regions. The sequence that is very closely associated with methylation of DNA is A. CG island. B. CAAT box. C. TATA box. D. CAP site. \(\mathbf{E}\). CTD.
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All of the following describe an operon except A. it is a control mechanism for eukaryotic genes. B. it includes structural genes. C. it is expected to code for polycistronic mRNA. D. it contains control sequences such as an operator. E. it can have multiple promoters.
In an operon, A. cach gene of the operon is regulated independently. B. control may be exerted via induction or via repression. C. operator and promoter may be trans to the genes they regulate. D. the structural genes are either not expressed ar all or fully expressed. E. control of gene expression consists exclusively of induction and repression.
The problem of pathogenic bacteria becoming resistant to a large number of antibiotics is a serious public health concern. A bacterial strain in a paticnt being treated with one antibiotic may suddenly become resistant not only to that antibiotic but to others as well even though it has not been exposed to the other antibiotics. This occurs when the bacteria acquire a plasmid from another strain that contains several different transposons. All of the following phrases describe transposons except A. a means for the permanent incorporation of antibiotic resistance into the bacterial chromosome. B. contain short inverted terminal repeat sequences. C. code for an enzyme that synthesizes guanosine tetraphosphate and guanosine pentaphosphate, which inhibit further transposition. D. include at least one gene that codes for a transposase. E. contain varying numbers of genes.
In eukaryotic transcription by RNA polymerase II, formation of a preinitiation complex A. begins with the binding of a protein (TBP) to the TATA box of the promoter. B. involves the ordered addition of several transcription factors and the RNA polymerase. C. allows an ATP-dependent opening of the two strands of DNA. D. requires that the C-terminal domain of RNA polymerase II not be phosphorylated. E. all of the above.
The \(E\). coli lacZYA region will be upregulated if A. there is a defect in binding of the inducer to the product of the Lad gene. B. glucose and lactose are both present, but the cell cannot bind the CAP protein. C. glucose and lactose are both readily available in the growth medium. D. the operator has mutated so it can no longer bind the repressor. E. the Lac corepressor is not present.
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