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Chapter 2: Problem 8

Another unusual form of DNA is a triple-stranded complex. Triple-stranded DNA A. gencrally occurs in DNA in regions that play no role in transcription. B. involves Hoogsteen hydrogen bonding. C. is characterized by the presence of a string of alternating purine- pyrimidine bases. D. forms only intermolecularly. E. assumes a cruciform conformation.

Short Answer

Expert verified
Answer: Triple-stranded DNA involves Hoogsteen hydrogen bonding.

Step by step solution

01

Understand Option A

Option A states that triple-stranded DNA generally occurs in regions that play no role in transcription. This statement is incorrect, as triple-stranded DNA can form in areas of the genome that play a role in gene regulation, such as in promoter regions.
02

Understand Option B

Option B states that triple-stranded DNA involves Hoogsteen hydrogen bonding. This statement is correct, as the third strand in triple-stranded DNA is held in place through Hoogsteen hydrogen bonding which is different from the regular Watson-Crick hydrogen bonding found in double-stranded DNA.
03

Understand Option C

Option C states that triple-stranded DNA is characterized by a string of alternating purine-pyrimidine bases. This statement is incorrect, as it is not a defining characteristic of triple-stranded DNA. Rather, it would be more accurate to say that triple-stranded DNA can form when a single-stranded DNA with excess purines or pyrimidines binds to a double-stranded DNA molecule.
04

Understand Option D

Option D states that triple-stranded DNA forms only intermolecularly. This statement is incorrect, as triple-stranded DNA can form both intramolecularly and intermolecularly.
05

Understand Option E

Option E states that triple-stranded DNA assumes a cruciform conformation. This statement is incorrect, as cruciform DNA is a different type of unusual DNA structure that arises when palindromic sequences within double-stranded DNA form hairpin-like structures.
06

Conclusion

Based on the analysis of each option, the correct statement about triple-stranded DNA is B (involves Hoogsteen hydrogen bonding).

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Most popular questions from this chapter

A nucleosome A. is a regularly repeating structure of DNA and histone proteins. B. has a core of DNA with proteins wrapped around the outside. C. uses only one rype of histone per nuclcosome. D. is separated from a second nucleosome by nonhistone proteins. E. has histones in contact with the major groove of the DNA.

In addition to superhelicity, DNA must be still further packaged to fit into the bacteria or cell. Which of the following is correct? A. Both prokaryotic and cukaryotic DNA form chromatin. B. A bacterial chromosome contains a single DNA molecule, but a human chromosome contains more than one DNA. C. Packaging of DNA into nucleosomes does not involve topoisomerases. D. Polysomes are the highest level of packaging DNA undergoes. E. Thirty-nm fibers (solenoids) can organize into a series of looped, condensed domains.

Which conformation of DNA, totally double helix, minimally unwound or largely unwound, would have the highest relative optical density at \(260 \mathrm{nm}\) ? Would a molecule of DNA having a higher content of guanine and cytosine than of adenine and thymine have a higher or lower \(T_{m}\) than one with the reverse composition?

Normally, certain kinds of reiterated scquences occur in a chromosome as an interspersion pattern that is A. highly repetitive DNA sequences. B. the portion of DNA composed of single-copy DNA. C. Alu sequences. D. alternating blocks of single-copy DNA and moderately repetitive DNA. E. alternating blocks of short interspersed repeats and long interspersed repeats.

An approach to reducing telomerase activity in tumor cells involves drugs that bind to G-quadroplex DNA since telomeres have the potential to form such structures. What is a G-quadroplex, and what about telomere structure might lead to it?
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