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Calmodulin is A. a nonspecific kinase. B. a protein that binds \(\mathrm{Ca}^{2+}\). C. a second messenger. D. an activator of nitric oxide synthase. E. a protein channel that facilitates the influx of \(\mathrm{Ca}^{2+}\).

Short Answer

Expert verified
Answer: The primary function of Calmodulin is to bind with \(\mathrm{Ca}^{2+}\) ions, allowing it to play an essential role in regulating various cellular processes.

Step by step solution

01

Option A: a nonspecific kinase

Calmodulin is not a nonspecific kinase. A kinase is an enzyme that modifies other proteins by adding phosphate groups to them, but Calmodulin doesn't have this function.
02

Option B: a protein that binds \(\mathrm{Ca}^{2+}\)

Calmodulin is a calcium-binding protein that plays an essential role in several cellular processes. It can bind to and regulate the function of various target proteins in response to changes in calcium levels.
03

Option C: a second messenger

Second messengers are small molecules or ions that relay signals from receptors on the cell surface to target molecules inside the cell. Calmodulin is not a second messenger but rather a protein that binds to them to regulate cellular processes.
04

Option D: an activator of nitric oxide synthase

Nitric oxide synthase (NOS) is an enzyme that produces nitric oxide, a molecule involved in several physiological processes. Calmodulin can bind to NOS and regulate its activity. However, defining Calmodulin solely as an activator of NOS would be too narrow.
05

Option E: a protein channel that facilitates the influx of \(\mathrm{Ca}^{2+}\)

Calmodulin does not form a protein channel. Instead, it's a calcium-binding protein that can modulate the activity of other proteins in response to changes in calcium concentration. Based on the analysis, the correct answer is: B. a protein that binds \(\mathrm{Ca}^{2+}\).

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Most popular questions from this chapter

The ErbB/HER family of receptor tyrosine kinase genes are linked to many different types of human cancers. Overexpression of any of these genes would lead to an increase in the various receptors. ErbB2 encodes the HER2 protcin. This receptor does not bind any known extracellular growth factor, but it does form dimers with other growth-factor-bound HER receptors. Even modest overexpression of HER2 can alter normal cell growth regulation. Ras protein is a critical regulator in cell proliferation, and its activity is enhanced by activated tyrosine kinase. Elements of its action include all of the following except A. formation of cyclic GMP. B. adaptor proteins binding to phosphorylated ryrosines on receptor tyrosine kinase. C. recruitment and stimulation of Ras-activating protein. D. exchange of GDP for GTP on the Ras protein. E. initiation of a cascade in which several kinases are activated sequentially by phosphorylation.

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The ErbB/HER family of receptor tyrosine kinase genes are linked to many different types of human cancers. Overexpression of any of these genes would lead to an increase in the various receptors. ErbB2 encodes the HER2 protcin. This receptor does not bind any known extracellular growth factor, but it does form dimers with other growth-factor-bound HER receptors. Even modest overexpression of HER2 can alter normal cell growth regulation. Which of the following statements about receptor tyrosine kinases is correct? A. The catalytic domain is on the N-terminal end. B. Activation of the kinase requires ATP. C. Growth factor binding to the receptor triggers dimerization which activates the kinase activity. D. Active tyrosine kinase can phosphorylate other proteins but not itself. E. All of the above.

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