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Explain how slinization reduces tailing of chromatographic peaks.

Short Answer

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Silanization creates hydroxyl groups that can form strong hydrogen bonds.

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We will explain how slinization can reduce chromatographic peak tailing in this task.

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- the process of applying alkoxysilane molecules to a surface.

- By blocking the silanol groups with nonpolar trimethylsilyl groups, this technique reduces tailing.

- It's called end-capping because silanization can cap hydroxyl groups that can create strong hydrogen bonds, which reduces chromatographic peak tailing.

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Most popular questions from this chapter

A Gas chromatogram of a mixture of toluene and ethyl acetate is shown here:

(a)Use the width of each peak (measured at the base)to calculate the number of theoretical plates in the column. Estimate all lengths to the nearest 0.1 mm.

(b)Using the width of the toluene peak at its base, calculate the width expected at half height. Compare the measured and calculated values. When the thickness of the the line is significant relative to the length being measured, it is important to take the pen line width into account. You can measure from the edge of one line to the corresponding edge of the other line,as shown here.

An open tubular column has an inner diameter of 207ฮผmand the thickness of the stationary phase on the inner wall is 0.50ฮผm. Unretained solute passes through in 63s and a particular solute emerges in 433s . Find the partition coefficient for this solute and find the fraction of time spent in the stationary phase.

A chromatogram with ideal Gaussian bands hastr=9minand
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(b) Find the plate height if the column is 10cm long.

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23-41. Describe how nonlinear partition isotherms lead to non-Gaussian band shapes. Draw the chromatographic peak shapes produced by an overloaded gas chromatography column and an overloaded liquid chromatography column.

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