Question

Which of the following columns will provide:

(a) highest number of plates?

(b) greatest retention?

(c) highest relative retention?

(d) best separation?

$$\begin{gathered} \mathbf{Column}\mathbf{}\mathbf{1}\mathbf{}\mathbf{:}\mathbf{}\mathbf{N}\mathbf{=}\mathbf{1000}\mathbf{;}{\mathbf{k}}_{\mathbf{2}}\mathbf{=}\mathbf{3}\mathbf{.}\mathbf{9}\mathbf{;}\mathbf{\alpha }\mathbf{=}\mathbf{1}\mathbf{.}\mathbf{16}\mathbf{;}\mathbf{}\mathbf{resolution}\mathbf{=}\mathbf{0}\mathbf{.}\mathbf{6} \\ \mathbf{Column}\mathbf{}\mathbf{2}\mathbf{}\mathbf{:}\mathbf{}\mathbf{N}\mathbf{=}\mathbf{5000}\mathbf{;}{\mathbf{k}}_{\mathbf{2}}\mathbf{=}\mathbf{3}\mathbf{.}\mathbf{9}\mathbf{;}\mathbf{\alpha }\mathbf{=}\mathbf{1}\mathbf{.}\mathbf{06}\mathbf{;}\mathbf{}\mathbf{resolution}\mathbf{=}\mathbf{0}\mathbf{.}\mathbf{8} \\ \mathbf{Column}\mathbf{}\mathbf{3}\mathbf{}\mathbf{:}\mathbf{}\mathbf{N}\mathbf{=}\mathbf{500}\mathbf{;}\mathbf{}\mathbf{}{\mathbf{k}}_{\mathbf{2}}\mathbf{=}\mathbf{4}\mathbf{.}\mathbf{7}\mathbf{;}\mathbf{\alpha }\mathbf{=}\mathbf{1}\mathbf{.}\mathbf{31}\mathbf{;}\mathbf{}\mathbf{resolution}\mathbf{=}\mathbf{1}\mathbf{.}\mathbf{1} \\ \mathbf{Column}\mathbf{}\mathbf{4}\mathbf{}\mathbf{:}\mathbf{}\mathbf{N}\mathbf{=}\mathbf{2000}\mathbf{;}{\mathbf{k}}_{\mathbf{2}}\mathbf{=}\mathbf{2}\mathbf{.}\mathbf{4}\mathbf{;}\mathbf{\alpha }\mathbf{=}\mathbf{1}\mathbf{.}\mathbf{24}\mathbf{;}\mathbf{}\mathbf{resolution}\mathbf{=}\mathbf{1}\mathbf{.}\mathbf{5} \end{gathered}$$

Short answer

The solution is

- a) Column 2 because it has the biggest N value (N = 5000)

- b) Column 3 because it has the largest ${\mathrm{k}}_2$value $\left({\mathrm{k}}_2=4.7\right)$

- c) Column 3 because it has the largest role="math" localid="1654934451145" $\mathrm{\alpha }$value $\left(\mathrm{\alpha }=1.31\right)$

- d) Column 4 because it is the only one with baseline resolution (resolution = 1.5)

Step-by-step solution

of 3

In this task we will determine which of the columns will provide:

a) highest number of plates

b) greatest retention

c) highest relative retention

d) best separation

of 3

$$\begin{gathered} \mathrm{Column}1:\mathrm{N}=1000;{\mathrm{k}}_2=1.2;\mathrm{\alpha }=1.16;\mathrm{resolution}=0.6 \\ \mathrm{Column}2:\mathrm{N}=5000;{\mathrm{k}}_2=3.9;\mathrm{\alpha }=1.06;\mathrm{resolution}=0.8 \\ \mathrm{Column}3:\mathrm{N}=500;{\mathrm{k}}_2=4.7;\mathrm{\alpha }=1.31;\mathrm{resolution}=1.1 \\ \mathrm{Column}4:\mathrm{N}=2000;{\mathrm{k}}_2=2.4;\mathrm{\alpha }=1.24;\mathrm{resolution}=1.5 \end{gathered}$$

of 3

The solution is

- a) Column 2 because it has the biggest N value (N = 5000)

- b) Column 3 because it has the largest ${\mathrm{k}}_2$value $\left({\mathrm{k}}_2=4.7\right)$

- c) Column 3 because it has the largest $\mathrm{\alpha }$value $\left(\mathrm{\alpha }=1.31\right)$

- d) Column 4 because it is the only one with baseline resolution (resolution = 1.5)