Question

Question: How do additives such as trienthylamine reduce tailing of certain solutes?

Short answer

Additives such as trienthylamine reduce tailing of certain solutes.

They are used to mask free silanol groups.which improves peak shape by masking adsorption sites. Solutes are strongly bound to additives, which reduces tailing. Solutes are held strongly to additives which reduces their tailing.

Step-by-step solution

definition of silanol

Silanols have been used as nucleophilic partners in transition-metal catalysed carbon–carbon cross-coupling reactions, organocatalysts for carbonyl compound activation reactions, intramolecular guiding groups for C–H bond activation reactions, enzyme inhibitors, and bioactive compound isosteres.

They are used to mask free silanol groups.

which improves peak shape by masking adsorption sites.

Solutes are strongly bound to additives, which reduces tailing.

strongly additives

Solutes are held strongly to additives which reduces their tailing.

Hence,

They are used to mask free silanol groups which improves peak shape by masking adsorption sites. Solutes are strongly bound to additives, which reduces tailing. Solutes are held strongly to additives which reduces their tailing.