Question

Name two general methods for improving the resolution of two substances on a chromatographic column.

Short answer

Lengthening the length of the column, and Changing the selective factor by altering the column packing are two general methods for improving the resolution of two substances on a chromatographic column.

Step-by-step solution

Step1. Given information

The two general methods which are used for improving the resolution of two substances on a chromatographic column should be named.

Step2. Chromatographic column

A chromatographic column is a vertically oriented tube made of plastic or glass. The stationary phase is contained by the column, which only enables the mobile phase to pass through.

Step3. Two general methods to improve resolution.

The separation of two close chromatographic peaks from one another is measured as resolution. A better resolution is required for accurate analysis.

Low resolutions can be upgraded using a variety of techniques. The following are the two general approaches for increasing the resolution of two compounds on a chromatographic column:

1. Altering the column packing to change the selection factor.
2. Increasing the column's length.