Question

Give an mRNA sequence that will code for the synthesis of metenkephalin.

Tyr-Gly-Gly-Phe-Met

Short answer

The mRNA sequence that will code for the synthesis of metenkephalin is,

• UAA GGG GGG UUU AUG
• UAC GGG GGG UUU AUG
• UAA GGA GGG UUU AUG
• UAC GGA GGG UUU AUG
• UAA GGA GGC UUC AUG
• UAA GGC GGU UUU AUG
• UAC GGA GGC UUC AUG
• UAC GGC GGU UUU AUG
• UUU GGA GGU UUC AUG

Step-by-step solution

Introduction

TranscribingDNA into mRNA is a complex process. Codons, which are tripeptide sequences that code for specific amino acids in the protein, are found in the mRNA.

Tripeptide sequence of codon

The sequence of codons has the following characteristics:

The requirements for the first two nucleotide positions are quite stringent.

Because the nucleotide's third position is a variation, a shift in the tripeptide third nucleotide does not always signal a change in the amino acidincorporated.

Tabulation for the amino acid codon

Amino acid	Codons
Tyr	UAA, UAC
Gly	GGU, GGA, GGC, GGG
Phe	UUU, UUC
Met	AUG

The codons are in$5^{\text{'}} \text{to} 3^{\text{'}}$ direction is,

• UAA GGG GGG UUU AUG
• UAC GGG GGG UUU AUG
• UAA GGA GGG UUU AUG
• UAC GGA GGG UUU AUG
• UAA GGA GGC UUC AUG
• UAA GGC GGU UUU AUG
• UAC GGA GGC UUC AUG
• UAC GGC GGU UUU AUG
• UUU GGA GGU UUC AUG

There are several mRNA sequencewhich will translate to give the given peptide sequence.