Chapter 20: Q30E (page 678)
In the Ritter reaction, an alkene reacts with a nitrile in the presence of strong aqueous sulfuric acid to yield an amide. Propose a mechanism.
Short Answer
A mechanism of Ritter reaction is shown below
Chapter 20: Q30E (page 678)
In the Ritter reaction, an alkene reacts with a nitrile in the presence of strong aqueous sulfuric acid to yield an amide. Propose a mechanism.
A mechanism of Ritter reaction is shown below
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Get started for freeHow could you convert each of the following compounds into butanoic acid? Write each step showing the reagents needed.
(a) 1-Butanol
(b) 1-Bromobutane
(c) 1-Butene
(d) 1-Bromopropane
(e) 4-Octene
Predict the product (s) and provide the mechanism for each reaction below.
How would you prepare 1-phenyl-2-butanone, C6H5CH2COCH2CH3, from benzyl
bromide, C6H5CHโBr? More than one step is required?
How would you prepare the following carbonyl compounds from a nitrile?
Isocitric acid, an intermediate in the citric acid cycle of food metabolism, has the systematic name (2R,3S)-3-carboxy-2-hydroxypentane-dioic acid. Draw the structure.
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