Question

How would you prepare the following compounds using either an Acetoacetic ester synthesis or a malonic ester synthesis?

Short answer

The compounds (a) and (c) are prepared by malonic ester synthesis. The compounds (b) and (d) are prepared by acetoacetic ester synthesis.

Step-by-step solution

Preparation of compound (a)

The given compound is prepared by malonic ester synthesis. The preparation is as follows,

Preparation of compound (b)

The given compound is prepared by acetoacetic ester synthesis. The preparation is as follows,

Preparation of compound (c)

The given compound is prepared by malonic ester synthesis.The preparation is as follows,

 Step 4: Preparation of compound (d)

The given compound is prepared by acetoacetic ester synthesis. The preparation is as follows,