Question

Question: Tyramine is an alkaloid found in mistletoe and ripe cheese. Dopamine is a neurotransmitter involved in the regulation of the central nervous system.

Tyramine dopamine

1. How can tyramine be prepared from β -phenylethylamine?
2. How can dopamine be prepared from tyramine?
3. Give two ways to prepare β -phenylethylamine from β -phenylethyl chloride.
4. How can β -phenylethylamine be prepared from benzyl chloride?
5. How can β - phenylethylamine be prepared from benzaldehyde?

Short answer

The answer is,

a.

Reaction

b.

Reaction

c.

Reaction

d.

Reaction

e.

Reaction

Step-by-step solution

Tyramine and Dopamine

The tyramine is a compound containing a hydroxyl group and ethylamine cation substituted on a benzene ring. The dopamine is a compound containing a two hydroxyl groups and ethylamine cation substituted on a benzene ring.

Subpart (a)

The reaction for the synthesis of tyramine from β-phenylethylamine is given below.

Reaction

Subpart (b)

The reaction for the synthesis of dopamine from tyramine is given below.

Reaction

Subpart (c)

The reaction for the preparation of β-phenylethylamine from β-phenylethyl chloride is given below.

Reaction

Subpart (d)

The reaction for the preparation of β-phenylethylamine from benzyl chloride is given below.

Reaction

Subpart (e)

The reaction for the preparation of β-phenylethylamine from benzaldehyde is given below.

Reaction