Question

Use retrosynthetic analysis to plan a synthesis of the following target molecules. The only carbon-containing compounds available for the syntheses are cyclohexanol, ethanol, and carbon dioxide.

(a)

(b)

(c)

(d)

Short answer

Answer:

(a)

(b)

(c)

(d)

Step-by-step solution

Retrosynthesis

Retrosynthesis is defined as a logical approach for designing an organic synthesis which involves a breaking down of target molecules into available or given starting material by the imaginary breaking of bonds.

Retrosynthesis of the following given compounds

(a)The simplest way to find the starting material is to carry out disconnection by the reverse ozonolysis and Diels-Alder reaction.

(b) The simplest way to find the starting material in (b) is to carry out disconnection by the reverse reaction of Gilman’s reagent and bromination.

(c) The simplest way to find the starting material in (c) is to carry out disconnection by the reverse reaction with Grignard reagent is shown below:

(d) The simplest way to find the starting material in (d) is to carry out disconnection by the reverse reaction with Grignard reagent is shown below: