Chapter 21: Q27P (page 1004)
Draw the resonance contributors of the peptide bond in the less stable configuration.
Chapter 21: Q27P (page 1004)
Draw the resonance contributors of the peptide bond in the less stable configuration.
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Get started for freea.Which amino acid has the lowest pI value?
b.Which amino acid has the highest pI value?
c.Which amino acid has the greatest amount of negative charge at pH = 6.20?
d.Which amino acid has a greater negative charge at pH = 6.20, glycine or methionine?
a. Calculate the overall yield of bradykinin when the yield for the addition of each amino acid to the chain is 70%.
b. What would be the overall yield of a peptide containing 15 amino acids if the yield for the incorporation of each is 80%?
Alanine has pKa values of 2.34 and 9.69. Therefore, alanine exists predominately as a zwitterion in an aqueous solution with pH > ____ and pH < ____.
A decapeptide undergoes partial hydrolysis to give peptides whose amino acid composition is shown. Reaction of the intact decapeptide with Edmanโs reagent releases PTH-Gly. What is the sequence of the decapeptide?
1.Ala, Trp
2. Val,Pro,Asp
3. Pro, Val
4. Ala, Glu
5. Trp, Ala, Arg
6.Arg, Gly
7.Glu, Ala, Leu
8. Met, Pro, Leu, Glu
Which is the more effective buffer at physiological pH, a solution of 0.1 M glycylglycine or a solution of 0.2 M glycine?
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