Question

What products would you expect from the following Suzuki coupling reactions?

Short answer

⦁ The product expected from the first reaction:

⦁ The product expected from the second reaction:

Step-by-step solution

Suzuki Reaction

Suzuki reaction is a type of metal catalyst reaction in which palladium metal catalyst has been used to do the coupling reaction.

The main compound used in this reaction is the base with hydroxide or carbonate ions. The other necessary reactant used in this reaction is an organoboron compound.

Subpart (a) The product expected from the given coupling Suzuki Reaction.

Ary halide reacting 1-Bromo-4-(tert-butyl)benzene with aryl boronic acid with the help of palladium-catalyzed substitution couples the carbon of two aryl rings to form the 4’-(tert-butyl)-a 2-methyl-1,1’-biphenyl product, which is a conjugated biaryl system.

Formation of 4’-(tert-butyl)-a 2-methyl-1,1’-biphenyl

Subpart (b) The product expected from the given coupling Suzuki Reaction.

Ary halide (Bromobenzene) reacts with aryl boronate ester with the help of palladium-catalyzed substitution reaction that couples the two aryl rings to form the product 3-phenyl pyridine, which is a conjugated biaryl system.

Formation of 3- phenyl pyridine