Question

Predict the products of these reaction sequences.

Short answer

LDA is the lithium di-isopropylamide. It is the strong base used to protonate the acidic hydrogen to form lithium enolate.

Step-by-step solution

Step-by-Step Solution Step 1: Reaction with LDA

LDA is the lithium di-isopropylamide. It is the strong base used to protonate the acidic hydrogen to form lithium enolate.

Acylation of the enolate ion

In reaction with the LDA formation of lithium, enolate occurs, followed by the reaction with acyl chloride formation of the acylated product occur.

Formation of the product

The mechanism for the product formation followed as

Product Formation