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The following structure is drawn in an unconventional manner.

(a) Label the N terminus and the C terminus.

(b) Label the peptide bonds.

(c) Identify and label each amino acid present.

(d) Give the full name and the abbreviated name

Short Answer

Expert verified

Peptide bonds are denoted by asterisk (*)

Step by step solution

01

Step-1: Explanation to part (a)

N-terminus is referred to as the free amine end of the peptide chain and free carboxylic acid end is referred to as the C-terminus. Both the termini are different from each other with respect to chemical properties.

02

Step-2: Explanation to part(b)

Peptide bonds are formed when the amine group of one amino acid forms bond with carbonyl carbon of another amino acid. A chain of amino acids is known as polypeptide.

Peptide bonds are denoted with asterisks (*)

03

Step-3: Explanation to part(c)

Amino acids are building blocks of protein molecules. Proteins are broken or digested down into smaller molecules known as amino acids.

04

Step-4: Explanation to part (d)

Full name of the given polypeptide is glycylglutaminylisoleucinamide. Its abbreviated name is Gly-Gln-Ile. Naming of the polypeptide is done from N-terminus to C-terminus.

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Most popular questions from this chapter

Draw three-dimensional representation of the following amino acids:

(a) L-alanine

(b) L-Leucine

(c) D-serine

(d) D-glutamine

Suggest how you would separate the free L-amino acid from its acylated D enantiomer in Figure 24-5.

Use resonance forms to show delocalization of the negative charge in Ruhemannโ€™s purple anion.

After treatment with peroxyformic acid, the peptide hormone vasopressin is partially hydrolyzed. The following fragments are recovered. Propose a structure for vasopressin.

Phe-Gln-Asn Pro-Arg-Gly.NH2 Cys-Tyr-Phe

Asn-Cys-Pro-Arg Tyr-Phe-Gln-Asn

Peptides often have functional groups other than free amino groups at the N terminus and other than carboxyl groups at the C terminus.

(a) A tetrapeptide is hydrolyzed by heating with 6 M, and the hydrolysate is found to contain Ala, Phe, Val, and Glu. When the hydrolysate is neutralized, the odor of ammonia is detected. Explain where this ammonia might have been incorporated in the original peptide.

(b) The tripeptide thyrotropic hormone releasing factor(TRF) has the full name pyroglutamylhistidylprolinamide. The structure appears here. Explain the functional groups at the N terminus and at the C terminus.

(c)On acidic hydrolysis, an unknown pentapeptide gives glycine, alanine, valine, leucine and isoleucine. No odor of ammonia is detected when the hydrolysate is neutralized. Reaction with phenyl isothiocyanate followed by mild hydrolysis gives nophenylthiohydantoin derivative. Incubation with carboxypeptidase has no effect. Explain these findings.

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