Chapter 28: Problem 4
Here is a portion of the nucleotide sequence in phenylalanine tRNA. $$ \text { 3'-ACCACCUGCUCAGGCCUU-5' } $$ Write the nucleotide sequence of its DNA complement.
Chapter 28: Problem 4
Here is a portion of the nucleotide sequence in phenylalanine tRNA. $$ \text { 3'-ACCACCUGCUCAGGCCUU-5' } $$ Write the nucleotide sequence of its DNA complement.
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Get started for freeThe alpha chain of human hemoglobin has 141 amino acids in a single polypeptide chain. Calculate the minimum number of bases on DNA necessary to code for the alpha chain. Include in your calculation the bases necessary for specifying termination of polypeptide synthesis.
Compare the codons with a purine, either \(\mathrm{A}\) or \(\mathrm{G}\), as the second base. Do the majority of the amino acids specified by these codons have hydrophilic or hydrophobic side chains?
Write the DNA complement for 5'-TCAACGAT-3'.
If you read J. D. Watson's account of the discovery of the structure of DNA, The Double Helix, you will find that for a time in their model-building studies, he and Crick were using alternative (and incorrect, at least in terms of their final model of the double helix) tautomeric structures for some of the heterocyclic bases. (a) Write at least one alternative tautomeric structure for adenine. (b) Would this structure still base-pair with thymine, or would it now base- pair more efficiently with a different base? If so, identify that base.
Compare the structural formulas of the aromatic amino acids phenylalanine and tyrosine. Also compare the codons for these two amino acids.
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