Chapter 23: Problem 2
Write structural formulas for these amines. (a) 2-Methyl-1-propanamine (b) Cyclohexanamine (c) \((R)-2\)-Butanamine
Chapter 23: Problem 2
Write structural formulas for these amines. (a) 2-Methyl-1-propanamine (b) Cyclohexanamine (c) \((R)-2\)-Butanamine
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Get started for freeFollowing is an outline for a synthesis of the anorexic (appetite suppressant)
fenfluramine. This compound was one of the two ingredients in Phen-Fen, a
weight-loss preparation now banned because of its potential to cause
irreversible heart valve damage.
Write the IUPAC and, where possible, a common name for each compound.
Several diamines are building blocks for the synthesis of pharmaceuticals and agrochemicals. Show how both 1,3 -propanediamine and 1,4-butanediamine can be prepared from acrylonitrile.
In Example 23.15, you considered the product of Cope elimination from the \(2 R, 3 S\) stereoisomer of 2-dimethylamino-3-phenylbutane. What is the product of a Cope elimination from the following stereoisomers? What is the product of a Hofmann elimination from each stereoisomer? (a) \(2 S, 3 R\) stereoisomer (b) \(2 S, 3 S\) stereoisomer
Epinephrine is a hormone secreted by the adrenal medulla. Among its actions,
it is a bronchodilator. Albuterol, sold under several trade names, including
Proventil and Salbumol, is one of the most effective and widely prescribed
antiasthma drugs. The \(R\) enantiomer of albuterol is 68 times more effective
in the treatment of asthma than the \(S\) enantiomer.
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