Chapter 6: Problem 6.28 (page 241)
Classify each transformation as substitution, elimination, or addition.
a.
b.
Short Answer
Answer
- Elimination reaction
- Addition reaction
Chapter 6: Problem 6.28 (page 241)
Classify each transformation as substitution, elimination, or addition.
a.
b.
Answer
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Get started for freePGF2α (Section 4.15) is synthesized in cells using a cyclooxygenase enzyme that catalyzesa multistep radical pathway. Two steps in the pathway are depicted in the accompanying equations.
(a) Draw in curved arrows to illustrate how C is converted to D in Step [1].
(b) Identify Y, the product of Step [2], using the curved arrows that are drawn on compound D.
Indicate which factors affect the rate of a reaction.
a. Which value corresponds to a negative value of or ?
b. In a unimolecular reaction with five times as much starting material as product at equilibrium, what is the value of Keq? Is positive or negative?
c. Which value corresponds to a larger : or ?
The use of curved arrows is a powerful tool that illustrates even complex reactions.
a. Add curved arrows to show how carbocation A is converted to carbocation B. Label each new bond formed. Similar reactions have been used in elegant synthesis of steroids.
b. Draw the product by following the curved arrows. This reaction is an example of a [3,3] sigma tropic rearrangement, as we will learn in chapter 27.
Given each value, determine whether the starting material or the product is favored at equilibrium.
a.
b.
c.
d.
e.
f.
g.
h.
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