Chapter 6: Problem 6.20 (page 233)
Draw an energy diagram for a two-step reaction, , where the relative energy of these compounds is , and the conversion of is rate-determining.
Short Answer
Answer
The energy diagram is as follows:
Chapter 6: Problem 6.20 (page 233)
Draw an energy diagram for a two-step reaction, , where the relative energy of these compounds is , and the conversion of is rate-determining.
Answer
The energy diagram is as follows:
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Get started for freePGF2α (Section 4.15) is synthesized in cells using a cyclooxygenase enzyme that catalyzesa multistep radical pathway. Two steps in the pathway are depicted in the accompanying equations.
(a) Draw in curved arrows to illustrate how C is converted to D in Step [1].
(b) Identify Y, the product of Step [2], using the curved arrows that are drawn on compound D.
Which bond in each pair has the higher bond dissociation energy?
a.
b.
Draw the structure for the transition state in each reaction.
a.
b.
The use of curved arrows is a powerful tool that illustrates even complex reactions.
a. Add curved arrows to show how carbocation A is converted to carbocation B. Label each new bond formed. Similar reactions have been used in elegant synthesis of steroids.
b. Draw the product by following the curved arrows. This reaction is an example of a [3,3] sigma tropic rearrangement, as we will learn in chapter 27.
Given each value, determine whether the starting material or the product is favored at equilibrium.
a.
b.
c.
d.
e.
f.
g.
h.
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