Question

Question: Synthesize each compound from diethyl malonate. You may use any other organic or inorganic reagents.

Short answer

Answer

The starting materials needed to prepare each compound are shown below.

Step-by-step solution

Malonic ester reaction

The malonic ester synthesis is a method required for the conversion of ethyl malonate to a carboxylic acid having one or two alkyl groups on the carbon

Retrosynthetic pathway for obtaining the starting materials

To obtain the starting materials, a retrosynthetic analysis is followed, as shown below.

Representation of the retrosynthetic approach of the product

Forward pathway for obtaining the product

To obtain the product, a forward reaction scheme analysis is followed and it is as shown below:

Representation of the forward pathway to obtain the product