Question

Question: What product is formed when each compound is treated first with LDA in THF solution at low temperature, followed by CH₃CH₂l?

Short answer

Answer

The products formed when each starting material is treated with LDA are shown below.

Step-by-step solution

Definition of LDA

LDA is a strong base that abstracts protons from the least hindered site of the target molecule.

The attached isopropyl groups with the nitrogen atom make it bulky, and hence, they always act as a base. They withdraw protons from the least hindered source.

Given reactions

The products formed in each of the reactions are shown below.

Reaction a

Reaction b

Reaction c