Question

What ester and Grignard reagent are needed to prepare each alcohol?

a.

b.

c.

Short answer

Answer

The ester and Grignard reagent needed to prepare each alcohol are shown in the following method:

a.

b.

c.

Step-by-step solution

Step-by-Step Solution Step 1: Use of Grignard reagent

The Grignard reagent is used in many nucleophilic addition reactions to get products such as aldehydes and alcohol.

Necessity of using two equivalents of Grignard reagent

It requires two equivalents of Grignard reagent to get alcohols as a product from the carboxylic acid derivatives starting materials. If you use one equivalent of the reagent, then the reaction will stop after forming an aldehyde.

Choosing the carbonyl compound

To select the correct ester and Grignard reagents, one must follow the retrosynthetic pathway.

The starting materials required to prepare alcohol a. are:

Preparation of a.

The starting materials required to prepare alcohol b. are:

Preparation of b.

The starting materials required to prepare alcohol c. are:

Preparation of c.