Chapter 24: Q.35. (page 962)
Question: What dicarbonyl compound is needed to prepare each compound by an intramolecular aldol reaction?
Short Answer
Answer
Chapter 24: Q.35. (page 962)
Question: What dicarbonyl compound is needed to prepare each compound by an intramolecular aldol reaction?
Answer
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Get started for freeQuestion:What starting materials are needed to synthesize each compound using a Robinson annulation?
Question: What product is formed when a solution of A and B is treated with mild base? This reaction is the first step in the synthesis of rosuvastatin (sold as a calcium salt under the trade name Crestor), a drug used to treat patients with high cholesterol.
Question: 2-Pentylcinnamaldehyde, commonly called flosal, is a perfume ingredient with a jasmine-like odor. Flosal is an -unsaturated aldehyde made by a crossed aldol reaction between benzaldehyde and heptanal , followed by dehydration. Draw a stepwise mechanism for the following reaction that prepares flosal.
Question:One step in the synthesis of sitagliptin (Problem 17.14, a drug used to treat type 2 diabetes) involves reaction of the mixed anhydride A with B to form C. Draw a stepwise mechanism for this reaction.
Question: Draw a stepwise mechanism for the following reaction, which was used in the synthesis of ezetimibe (Section 20.6), a drug used to treat patients with high cholesterol.
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