Chapter 29: Q7. (page 1158)
What amino acid is formed whenis treated with the following series of reagents:
role="math" localid="1648630585393"
Short Answer
.
Chapter 29: Q7. (page 1158)
What amino acid is formed whenis treated with the following series of reagents:
role="math" localid="1648630585393"
.
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Get started for freeDraw the structure of each peptide. Label the N-terminal and C-terminal amino acids and all amide bonds.
a. Val–Glu
b. Gly–His–Leu
c. M–A–T–T
What aldehyde is needed to synthesize each amino acid by the Strecker synthesis?
(a) Valine;
(b) Leucine;
(c) Phenylalanine.
An octapeptide contains the following amino acids: Arg, Glu, His, Ile, Leu, Phe, Tyr, and Val. Carboxypeptidase treatment of the octapeptide forms Phe and a heptapeptide. Treatment of the octapeptide with chymotrypsin forms two tetrapeptides, A and B. Treatment of A with trypsin yields two dipeptides, C and D. Edman degradation cleaves the following amino acids from each peptide: Glu (octapeptide), Glu (A), Ile (B), Glue (C), and Val (D). Partial hydrolysis of tetrapeptide B forms Ile-Leu in addition to other products. Deduce the structure of the octapeptide and fragments A-D.
Draw the mechanism for the reaction that removes an Fmoc group from an amino acid under the following conditions:
Devise a stepwise synthesis of the tripeptide Val-leu-Val from 3-methylbutanal as the only organic starting material. You may also use any required inorganic or organic reagents.
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