Chapter 18: 5P (page 684)
What product is formed when benzene is treated with each organic halide in the presence of .
Chapter 18: 5P (page 684)
What product is formed when benzene is treated with each organic halide in the presence of .
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Get started for freeQuestion: Ibufenac, a para-disubstituted arene with the structure HO2CCH2C6H4CH2CH(CH3)2, is a much more potent analgesic than aspirin, but it was never sold commercially because it caused liver toxicity in some clinical trials. Devise a synthesis of ibufenac from benzene and organic halides having fewer than five carbons.
Question: Propose a structure of compound C (molecular formula ) consistent with the following data. C is partly responsible for the odor and flavor of raspberries. Compound C: IR absorption at 1717 cmโ1.
Question: Explain the reactivity and orientation effects observed in each heterocycle.
a. Pyridine is less reactive than benzene in electrophilic aromatic substitution and yields 3-substituted products.
b. Pyrrole is more reactive than benzene in electrophilic aromatic substitution and yields 2-substituted products.
Draw all products formed when m-chlorotoluene is treated with in
For each N-substituted benzene, predict whether the compound reacts faster than, slower than, or at a similar rate to benzene in electrophilic aromatic substitution. Then draw the major product (s) formed when each compound reacts with a general electrophile .
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