Question

What is the major product formed by an intramolecular Friedel–Crafts acylation of the following compound?

Short answer

The major product formed is as follows:

Step-by-step solution

Friedel-Craft acylation

Friedel-Craft acylation involves the action of an acetyl halide on an aromatic compound in the presence of anhydrous chloride.

Reaction

The 2D structure of the given 3D structure is as follows:

The given molecule contains two benzene rings, with one of them containing an electron releasing group $-{\text{OCH}}_{\text{3}}$.

Acylation is more favorable toward the benzene ring, which is an electron-releasing group.

Therefore, the product of the reaction is given as follows: