Chapter 29: Q5P (page 1157)
What-halo carbonyl compoundis needed to synthesize each amino acid?
(a) Glycine
(b) Isoleucine
(c) Phenylalanine
Short Answer
Answer
a.
b.
c.
Chapter 29: Q5P (page 1157)
What-halo carbonyl compoundis needed to synthesize each amino acid?
(a) Glycine
(b) Isoleucine
(c) Phenylalanine
Answer
a.
b.
c.
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Get started for freeDraw the structure of the N-phenylthiohydantoin formed by initial Edman degradation of each peptide: (a) Ala-Gly-Phe-Phe; (b) Val-Ile-Tyr.
What types of stabilizing interactions exist between each of the following pairs of amino acids?
a. Ser and Tyr
b. Val and Leu
c. two Phe residues
The enolate derived from diethyl acetamidomalonate is treated with each of the following alkyl halides. After hydrolysis and decarboxylation, what amino acid is formed?
a. CH3I
b. (CH3)2CHCH2Cl
c. CH3CH2CH(CH3)Br
a.(S)-Penicillamine, an amino acid that does not occur in proteins, is used as a copper chelating agent to treat Wilson’s disease, an inherited defect in copper metabolism.
(R)-Penicillamine is toxic, sometimes causing blindness. Draw the structures of (R) and (S)-penicillamine.
b. What disulfide is formed from oxidation of L-penicillamine?
The fibroin proteins found in silk fibers consist of large regions of β-pleated sheets stacked one on top of another. (a) Explain why having a glycine at every other residue allows the β-pleated sheets to stack on top of each other. (b) Why are silk fibers insoluble in water?
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