Question

What alkyl halide is needed to synthesize each amino acid from diethyl acetamidomalonate: (a)Asn; (b)His; (c)Trp?

Short answer

Alkyl halides are familiar with the name haloalkanes. They are acquired from alkanes comprising one or several halogens. Numerous alkyl halides are found, and one among them is the haloalkane.

Step-by-step solution

Step 1:Alkyl halide

Alkyl halides are familiar with the name haloalkanes. They are acquired from alkanes comprising one or several halogens. Numerous alkyl halides are found, and one among them is the haloalkane.

Amino acid

Amino acids constitute substances that link to create proteins. The human body utilizes amino acids to generate proteins. These proteins are essential for numerous functions like growth and restoring body tissue.

Alkyl halide needed to synthesize each amino acid from diethyl acetamidomalonate

The reaction of diethyl acetamidomalonate with alkyl halide leads to the generation of amino acids.

The steps involved in this process include abstraction of the acidic proton, enolate alkylation at the carbon, the hydrolysis of ester and amide, and decarboxylation of the alkylated product.

a. The alkyl halide needed to synthesize Asparagine (Asn) from diethyl acetamidomalonate can be given as:

b. The alkyl halide needed to synthesize Histidine (His) from diethyl acetamidomalonate can be given as:

c.The alkyl halide needed to synthesize tryptophan (Trp) from diethyl acetamidomalonate can be given as: