Chapter 29: Q36P (page 1192)
What is the predominant form of each of the following amino acids at pH=1? What is the overall charge on the amino acid at this pH?(a)threonine ; (b)methionine; (c)aspartic acid; (d)arginine
Chapter 29: Q36P (page 1192)
What is the predominant form of each of the following amino acids at pH=1? What is the overall charge on the amino acid at this pH?(a)threonine ; (b)methionine; (c)aspartic acid; (d)arginine
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Get started for freeDraw the organic products formed in the following reaction.
Draw the structure of the N-phenylthiohydantoin formed by initial Edman degradation of each peptide: (a) Ala-Gly-Phe-Phe; (b) Val-Ile-Tyr.
Draw the structure of leu-enkephalin, a pentapeptide that acts as an analgesic and opiate, and has the following sequence: TyrโGlyโGlyโPheโLeu. (The structure of a related peptide, met-enkephalin,
appeared in Section 22.6B.)
Give the amino acid sequence of an octapeptide that contains the amino acids Tyr, Ala, Leu (2 equiv), Cys, Gly, Glu and Val, and forms the following fragments when partially hydrolyzed with HCl: Val-Cys-Gly-Glu, Ala-Leu-Tyr, and Tyr-Leu-Val-Cys.
Explain why the pKaof the -NH3+group of an -amino acid is lower than the pKaof the ammonium ion derived from a amine . For example, pKaof the group of alanine is 9.87 but the pKaof is 10.63.
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