Chapter 21: 1P (page 817)
Rank the following compounds in order of increasing reactivity towards nucleophilic attack.
Chapter 21: 1P (page 817)
Rank the following compounds in order of increasing reactivity towards nucleophilic attack.
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Get started for free(a) Explain how in can reduce hemiacetal A to butane-1,4-diol (b) What product is formed when A is treated with ? (c) The drug isotretinoin is formed by the reaction of X and Y. What is the structure of isotretinoin? Although isotretinoin (trade name Accutane or Roaccutane) is used for the treatment of severe acne, it is dispensed under strict controls because it also causes birth defects
Draw a stepwise mechanism for the following imine hydrolysis
What starting materials are needed to prepare each alkene by a Wittig reaction? When there are two possible routes, indicate which route, if any, is preferred.
a.
b
c.
An unknown compound D exhibits a strong absorption in its IR spectrum at 1692 cm-1 . The mass spectrum of D shows a molecular ion at m/z = 150 and a base peak at 121. The 1H- NMR spectrum of D is shown below. What is the structure of D?
Draw the products of the following Wittig reactions
a.
b.
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