Problem 1
What features distinguish enzymes that undergo allosteric control from those that obey the Michaelis-Menten equation?
Problem 11
Does the behavior of allosteric enzymes become more or less cooperative in the presence of activators?
Problem 14
Distinguish between the concerted and sequential models for the behavior of allosteric enzymes.
Problem 21
What are three advantages of using allosteric drugs as opposed to orthosteric ones?
Problem 26
What amino acids are often phosphorylated by kinases?
Problem 27
What are some possible advantages to the cell in combining phosphorylation with allosteric control?
Problem 28
Explain how phosphorylation is involved in the function of the sodium- potassium ATPase.
Problem 29
Explain how glycogen phosphorylase is controlled allosterically and by covalent modification.
Problem 32
Name three proteins that are subject to the control mechanism of zymogen activation.
Problem 33
List three proteases and their sub-strates