Problem 52
What is a prion?
Problem 55
What are some diseases caused by misfolded proteins?
Problem 60
What aspects of the transmission of scrapie or other spongiform encephalopathies act like genetic diseases? What aspects act like transmittable diseases?
Problem 64
Why would doctors not want to just completely inhibit \(\beta\) -secretase in a patient with Alzheimer's disease?
Problem 65
Severe combined immunodeficiency disease (SCID) is characterized by the complete lack of an immune system. Strains of mice have been developed that have SCID. When SCID mice that carry genetic predisposition to prion diseases are infected with \(\operatorname{Pr} \mathrm{P}^{\text {ec }}\), they do not develop prion diseases. How do these facts relate to the transmission of prion diseases?
