Problem 39
In fatty-acid synthesis, malonyl-CoA, rather than acetyl-CoA, is used as a "condensing group." Suggest a reason for this
Problem 47
What structural feature do all steroids have in common? What are the biosynthetic implications of this common feature?
Problem 48
In steroid synthesis, squalene is oxidized to squalene epoxide. This reaction is somewhat unusual, in that both a reducing agent (NADPH) and an oxidizing agent (O \(_{2}\) ) are required. Why are both needed?
Problem 50
A drug that reduces blood cholesterol has the effect of stimulating the production of bile salts. How might this result in lower blood cholesterol? Hint: There are two ways.
Problem 51
What role does neuropeptide Y play in control of appetite? Where do its effects take place?
Problem 54
How does leptin affect the metabolism of lipids?
