Problem 34
Beriberi is a disease caused by a deficiency of vitamin \(\mathrm{B}_{1}\) (thiamine) in the diet. Thiamine is the precursor of thiamine pyrophosphate. In view of what you have learned in this chapter, why is it not surprising that alcoholics tend to develop this disease?
Problem 35
Most hunters know that meat from animals that have been run to death tastes sour. Suggest a reason for this observation.
Problem 37
Cancer cells grow so rapidly that they have a higher rate of anaerobic metabolism than most body tissues, especially at the center of a tumor. Can you use drugs that poison the enzymes of anaerobic metabolism in the treatment of cancer? Why, or why not?
Problem 41
What is the net gain of ATP molecules derived from the reactions of glycolysis?
Problem 46
What should be the net ATP yield for glycolysis when fructose, mannose, and galactose are used as the starting compounds? Justify your answer.
Problem 52
Why is the formation of fructose- \(1,6-\) bisphosphate a step in which control is likely to be exercised in the glycolytic pathway?
