Problem 2
RECALL A genetic code in which two bases encode a single amino acid is not adequate for protein synthesis. Give a reason why.
Problem 6
RECALL Describe the role of stop codons in the termination of protein synthesis.
Problem 8
REFLECT AND APPLY It is possible for the codons for a single amino acid to have the first two bases in common and to differ in the third base. Why is this experimental observation consistent with the concept of wobble?
Problem 10
REFLECT AND APPLY Is it reasonable that codons for the same amino acid have one or two nucleotides in common? Why or why not?
Problem 14
BIOCHEMICAL CONNECTIONS Explain how a frameshift in reading mRNA affects the translation of the mRNA for the IAV viral protease.
Problem 20
REFLECT AND APPLY Suggest a reason why the proofreading step in protein synthesis takes place at the level of amino acid activation rather than that of codon-anticodon recognition.
Problem 22
RECALL Identify the following by describing their functions: EF-G, EF-Tu, EF- Ts, EF-P, and peptidyl transferase.
Problem 24
RECALL What is the role of the 50 S ribosomal subunit in prokaryotic protein synthesis?
Problem 25
RECALL What are the A site and the P site? How are their roles in protein synthesis similar? How do they differ? What is the \(\mathbf{E}\) site?
Problem 26
RECALL How does puromycin function as an inhibitor of protein synthesis?
