Question

Consider the following segment of mRNA produced by the normal order of DNA nucleotides:

CUU AAA CGA CAU

a. What is the amino acid order produced from this mRNA?

b. What is the amino acid order if a point mutation changes from CUU to CCU?

c. What is the amino acid order if a point mutation changes from CGA to AGA?

d. What is the amino acid order of the insertion mutation adds a G to the beginning of the mRNA segment?

e. What is the amino acid order of the deletion mutation removes C to the beginning of the mRNA segment?

Short answer

a. N-Leu-Lys-Arg-His-C

b. N-Pro-Lue-Lys-Arg-His-C

c. N-Leu-Lys-Arg-Val-C

d. The new mRNA sequence is GCU UAA ACG ACA U

e. The new mRNA sequence is UUA AAC GAC AU

Step-by-step solution

Step1  : Part (a) Given information

The order of DNA nucleotide is:

CUU AAA CGA CAU

Part (a) Explanation

The table from the book is given which is as follows:

The order of DNA nucleotide is given as:

CUU AAA CGA CAU

Thus, using the values from the table the amino acid order produced from this mRNA is as follows:

N-Leu-Lys-Arg-His-C

where N represents the 5' terminal and C represents the 3' terminal.

Part (b) Explanation

The table from the book is given which is as follows:

The order of DNA nucleotide is given as:

CUU AAA CGA CAU

If a point mutation changes from CUU to CCU. Thus, using the values from the table the amino acid order produced from this mRNA is as follows:

N-Pro-Lue-Lys-Arg-His-C

where N represents the 5' terminal and C represents the 3' terminal.

Part (c) Explanation

The table from the book is given which is as follows:

The order of DNA nucleotide is given as:

CUU AAA CGA CAU

If a point mutation changes from CGA to AGA Thus, using the values from the table the amino acid order produced from this mRNA is as follows:

N-Pro-Lue-Lys-Arg-His-C

where N represents the 5' terminal and C represents the 3' terminal.

Part (d) Explanation

The table from the book is given which is as follows:

The order of DNA nucleotide is given as:

CUU AAA CGA CAU

if the insertion mutation adds a G to the beginning of the mRNA segment, Then, the new mRNA sequence is GCU UAA ACG ACA U which signifies N-Ala-STOP.

Part (d) Explanation

The table from the book is given which is as follows:

The order of DNA nucleotide is given as:

CUU AAA CGA CAU

If the deletion mutation removes C to the beginning of the mRNA segment. Then, the new mRNA sequence is UUA AAC GAC AU.