Question

Magnetic resonance spectroscopic imaging (MRSI) does not: a. help define the spatial heterogeneity of brain lesions. b. provide less useful information than single voxel spectroscopy for distinguishing radiation necrosis versus recurrent tumor. c. allow for accurate diagnosis of brain lesions. d. demonstrate the same metabolic peaks as single voxel spectroscopy.

Short answer

Answer: Provide less useful information than single voxel spectroscopy for distinguishing radiation necrosis versus recurrent tumor.

Step-by-step solution

Understand the concept of MRSI

Magnetic Resonance Spectroscopic Imaging (MRSI) is a non-invasive imaging technique that combines the spatial information of Magnetic Resonance Imaging (MRI) with the biochemical information provided by Magnetic Resonance Spectroscopy (MRS). MRSI is particularly useful in studying the metabolic characteristics of various brain lesions such as tumors and radiation necrosis.

Evaluate each option

Now, let's evaluate each option to see which one correctly identifies what MRSI does NOT do: a. help define the spatial heterogeneity of brain lesions: MRSI does help define the spatial heterogeneity of brain lesions by providing biochemical and metabolic information, combined with the spatial information provided by MRI. So, this statement is incorrect. b. provide less useful information than single voxel spectroscopy for distinguishing radiation necrosis versus recurrent tumor: MRSI has the advantage of studying larger areas of the brain compared to single voxel spectroscopy. MRSI provides more comprehensive information, allowing for better differentiation between radiation necrosis and recurrent tumors. Therefore, this statement is true. c. allow for accurate diagnosis of brain lesions: MRSI does allow for accurate diagnosis of brain lesions by providing detailed biochemical, metabolic, and spatial information. So, this statement is incorrect. d. demonstrate the same metabolic peaks as single voxel spectroscopy: MRSI and single voxel spectroscopy both utilize the same concepts of MRS, resulting in similar metabolic peaks. Thus, this statement is incorrect.

Choose the correct option

Since option b correctly identifies what MRSI does NOT do, the answer to this question is: Magnetic resonance spectroscopic imaging (MRSI) does not: b. provide less useful information than single voxel spectroscopy for distinguishing radiation necrosis versus recurrent tumor.