Chapter 46: Problem 9
Adjuvants typically fall into two major categories, which are a) vesicles and nanoparticles b) proteins and DNA c) live and attenuated d) vehicles and immunomodulators
Chapter 46: Problem 9
Adjuvants typically fall into two major categories, which are a) vesicles and nanoparticles b) proteins and DNA c) live and attenuated d) vehicles and immunomodulators
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Get started for freeIn addition to the ability to target antigens to \(\mathrm{C5a}\) receptor- bearing APCs, the conformationally-biased C5a agonists/molecular adjuvants induce C5a-like responses at the C5a receptor on the APC. Describe these C5a-like responses.
In addition to the ability to target antigens to C5a receptor-bearing APCs, the conformationally-biased C5a agonists/molecular adjuvants induce C5a-like responses at the C5a receptor on the APC. Describe these C5a-like responses.
Antigen presenting cells (APC) represent an important class of immune cells essential for generating an antigen-specific immune response. Briefly describe the basic cellular mechanism by which APCs contribute to this antigen-specific immune outcome.
The C-terminal region of complement-derived C5a (C5a65-74) represents a) the biologically active region of \(\mathrm{C} 5 \mathrm{a}\) b) a post-translational signal sequence c) a site for phosphorylation by kinases d) a immunogenic site recognized by T lymphocytes
The two principal biological effects of complement component C5a are a) intercalation of DNA and de novo protein synthesis b) inflammation and immune stimulation c) neo-vascularization and spleen development d) protease activation and carbohydrate clearance
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