Question

The two principal biological effects of complement component C5a are a) intercalation of DNA and de novo protein synthesis b) inflammation and immune stimulation c) neo-vascularization and spleen development d) protease activation and carbohydrate clearance

Short answer

Answer: Inflammation and immune stimulation.

Step-by-step solution

Understanding the complement component C5a

Complement component C5a is a biologically active cleavage product of the complement factor C5 that is involved in the immune response. It is a potent attractant for leukocytes (white blood cells) and plays a crucial role in inflammatory responses.

Analyzing each option provided

a) Intercalation of DNA and de novo protein synthesis - This option is not relevant to C5a as its primary function is in the immune response and attracting leukocytes. b) Inflammation and immune stimulation - This option is accurate as C5a is indeed involved in inflammation and immune responses, such as attracting leukocytes and activating cells like neutrophils and macrophages. c) Neo-vascularization and spleen development - While the immune system is related to these processes, it is not the primary function of C5a. So this option is not correct. d) Protease activation and carbohydrate clearance - This option seems unrelated to complement component C5a as its primary functions involve immune response and inflammation.

Select the correct option based on the analysis

As we analyzed each option, b) inflammation and immune stimulation seems to be the most accurate answer as it provides the principal biological effects of C5a in the immune response and inflammation.