Chapter 33: Problem 6
Microsatellites a. are relatively highly polymorphic genetic markers b. can by amplified by polymerase chain reactions c. contain repeated elements d. all of the above e. none of the above
Chapter 33: Problem 6
Microsatellites a. are relatively highly polymorphic genetic markers b. can by amplified by polymerase chain reactions c. contain repeated elements d. all of the above e. none of the above
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Get started for freeHuntington disease is an example of a dominantly inherited disease because a. two copies of the disease allele are needed to express the disease b. the disease locus is on the \(\mathrm{X}\) chromosome c. only one copy of the disease allele is needed to express the disease d. it exhibits classic anticipation e. it can only be inherited from an affected mother
Allelic genetic association analyses may find positive associations because the a. allele causes the disease b. allele is in strong linkage disequilibrium with the disease allele c. result is a false positive d. all of the above e. none of the above
Which of the following has been proposed as a candidate for susceptibility to amyotrophic lateral sclerosis? a. VEGF b. CNTF c. glutamate system d. all of the above e. none of the above
Characteristic of FTDP-17 is a. a phenotype that may be mistaken for \(\mathrm{AD}\) b. linkage to chromosome 17 c. abnormal Tau accumulation d. all of the above e. none of the above
Causative mutations in which of the following genes has been described in early-onset \(\mathrm{AD}\) ? a. amyloid precursor protein, presenilin-1, presenilin- 2 b. presenilin-1, amyloid precursor protein, apolipoprotein \(\mathrm{C}\) c. presenilin-1, presenilin-2, apolipoprotein \(C\) d. apolipoprotein C, presenilin-2, amyloid precursor protein e. huntingtin, presenilin-1, presenilin-2
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