Chapter 33: Problem 16
Characteristic of FTDP-17 is a. a phenotype that may be mistaken for \(\mathrm{AD}\) b. linkage to chromosome 17 c. abnormal Tau accumulation d. all of the above e. none of the above
Chapter 33: Problem 16
Characteristic of FTDP-17 is a. a phenotype that may be mistaken for \(\mathrm{AD}\) b. linkage to chromosome 17 c. abnormal Tau accumulation d. all of the above e. none of the above
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Get started for freePenetrance and expressivity refer to a. the proportion who get the disease and how the disease manifests respectively b. redundant terms c. how the disease manifests and the proportion who get the disease respectively d. all of the above e. none of the above
A characteristic of modern genetic research is a. that very few candidate genes are proposed for any given disorder b. that positive association studies of candidates have been consistently replicated c. all of the above d. none of the above
A modifier gene a. must cause disease. b. alters the expression of a disease. c. must be in linkage disequilibrium with the disease allele. d. all of the above. e. none of the above.
An advantage to using single nucleotide polymorphisms in genetic studies is that a. each marker is highly polymorphic b. they are common and distributed throughout the genome c. they are always within exons, and therefore cause a functional change d. all of the above e. none of the above
The genetics underlying multiple sclerosis are typical for a neurodegenerative disease in that a. concordance rates in monozygotic twins is higher than in dizygotic twins. b. linkage and association approaches have been used to identify likely candidates for a role in the disease c. there is an important environmental component to the disease d. all of the above e. none of the above
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