Question

Peripheral anti-viral immune responses control in measure HIV-1 CNS infection a. true b. false

Short answer

Answer: True

Step-by-step solution

Understand the question

Read the statements carefully and understand the topic related to HIV-1 infection in the CNS and peripheral anti-viral immune responses.

Role of peripheral anti-viral immune responses

Learn about the role of peripheral anti-viral immune responses in controlling HIV-1 infection. These responses help to control viral replication and dissemination in the periphery, making it crucial to prevent the virus from reaching the CNS.

HIV-1 infection in the CNS

Understand how HIV-1 can infect the CNS. The CNS is susceptible to HIV-1 infection due to a compromised blood-brain barrier in specific regions. The infection in the CNS can lead to severe neurological complications, called HIV-associated neurocognitive disorders (HAND).

Assess the statement "Peripheral anti-viral immune responses control in measure HIV-1 CNS infection"

Consider whether peripheral anti-viral immune responses can control the extent of HIV-1 infection in the CNS. Peripheral anti-viral immune responses play a significant role in limiting viral replication and dissemination, which contributes to controlling the virus from reaching the CNS. However, once HIV-1 enters the CNS, local immune responses are mostly responsible for controlling the infection. So, peripheral anti-viral immune responses can control the HIV-1 infection in the CNS to some extent, but not completely.

Choose the correct answer

Based on the understanding of the role of peripheral anti-viral immune responses in controlling HIV-1 infection in the CNS, choose the correct answer between true (a) and false (b). The correct answer is: a. true