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What does multisystemic neurodegeneration refer to?

Short Answer

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Answer: Multisystemic neurodegeneration refers to a disorder that affects multiple systems within the nervous system, resulting in the progressive decline or deterioration of the structure, function, and/or number of neurons. Examples of multisystemic neurodegeneration disorders include Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), Frontotemporal dementia (FTD), and Parkinson's disease.

Step by step solution

01

Understand the term "multisystemic"

The prefix "multi" means many or more than one, and "systemic" means related to a system or affecting multiple systems. In the context of multisystemic neurodegeneration, it implies that the condition affects multiple systems within the nervous system.
02

Understand neurodegeneration

Neurodegeneration refers to the progressive decline or deterioration of the structure, function, and/or number of neurons (nerve cells) in the brain and spinal cord. This can lead to the impairment or loss of various cognitive, motor, and/or other functions.
03

Combine the understanding of multisystemic and neurodegeneration

Combining the understanding of multisystemic and neurodegeneration, multisystemic neurodegeneration refers to a disorder that affects multiple systems within the nervous system, resulting in the progressive decline or deterioration of the structure, function, and/or number of neurons.
04

Provide examples of multisystemic neurodegeneration disorders

Examples of multisystemic neurodegeneration disorders include Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), Frontotemporal dementia (FTD), and Parkinson's disease. These disorders typically share common symptoms, such as movement difficulties, cognitive impairments, and autonomic dysfunction, resulting from the degeneration of neurons in multiple areas of the brain and spinal cord.

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Most popular questions from this chapter

Define the notion of non-cell autonomous neurodegeneration and provide an example.

Which of the following statements are always correct? a. Neurodegenerative diseases can involve either the central or the peripheral nervous systems, or both. b. A familial occurrence of a neurodegenerative disease is the signature of its genetic origin. c. Cardiovascular problems exacerbate the cognitive decline in patients with dementia and vise-versa. d. Neurodegenerative diseases are associated with a shortened life-span because they eventually impair respiratory or cardiovascular functions. e. When available, symptomatic agents normalize life-span in patients suffering from neurodegenerative diseases.

What is the correct statement about the neuropathology of neurodegenerative diseases? a. Neuropathologic changes in neurodegenerative diseases are always detectable in at least one region of the nervous system. b. Residual neurons look sick or normal. c. In addition to the loss of neurons, there is always some gliosis and protein aggregates. d. If different regions of the brain are affected, the type of neurons degenerating remains identical. e. The multisystemic nature of a neurodegenerative process is explained by a trans-synaptic phenomenon.

What are the three broad categories of diseases of the nervous system?

What are the two most prevalent neurodegenerative diseases? a. Alzheimer's disease and stroke b. Parkinson's disease and brain tumor c. Alaheimer's disease and Parkinson's disease d. Huntington's disease and amyotrophic lateral sclerosis e. Mitochondrial encephalopathy and multiple sclerosis

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