Question

Which of the following is NOT considered to be a major role of Müller cells? a. Spatial redistribution of potassium b. Neurotransmitter uptake and removal c. Homeostatic maintenance of retinal \(\mathrm{pH}\) levels d. Glycogen storage e. Promoting retinal adhesion to the back of the eye

Short answer

a. Spatial redistribution of potassium b. Neurotransmitter uptake and removal c. Homeostatic maintenance of retinal pH levels d. Glycogen storage e. Promoting retinal adhesion to the back of the eye Answer: d. Glycogen storage

Step-by-step solution

Introduction to Müller cells

Müller cells are a type of glial cell found in the retina of the vertebrate eye. They play vital roles in maintaining the structure and function of the retina. It is essential to understand their primary functions to identify which of the given options is not considered a major role of Müller cells.

Major roles of Müller cells

Müller cells have various functions, including: 1. Spatial redistribution of potassium ions: They help maintain the potassium ion balance in the retina by redistributing ions. 2. Neurotransmitter uptake and removal: They participate in recycling neurotransmitters by absorbing and metabolizing them. 3. Homeostatic maintenance of retinal pH levels: They help maintain proper pH levels in the retina. 4. Structural support: They provide structural support to the retina and assist in maintaining the organization of neural cells. 5. Promoting retinal adhesion to the back of the eye: They help secure the retina to the back of the eye, providing attachment and stability.

Comparing the given options against the primary functions

Now, let's compare each of the provided options with the major roles of Müller cells listed in step 2: a. Spatial redistribution of potassium - This is one of the primary functions of Müller cells. b. Neurotransmitter uptake and removal - This is another primary function of Müller cells. c. Homeostatic maintenance of retinal pH levels - This is another primary function of Müller cells. d. Glycogen storage - This role is not mentioned among the primary functions of Müller cells. e. Promoting retinal adhesion to the back of the eye - This is one of the primary functions of Müller cells.

Conclusion

Based on the comparison in step 3, we can conclude that option d, Glycogen storage, is NOT considered to be a major role of Müller cells.